Monday
Feb022009

Collaborative Research Efforts

There are often times when there is not enough hours in a day to initiate and complete all of those critical experiments which are an integral part of your research program.  DNA Diagnostics, Inc. offers laboratory support services, technical advice, and scientific consultation in a timely and economic manner. In partnership with other DNA typing laboratories, DNA Diagnostics, Inc. is dedicated to obtaining quality DNA test results based on sound science and applications. For more information on your potential research needs or goals contact us by phone or EMAIL us at DNADiagnosticsInc@gmail.com.

PROJECTS COMPLETED:

  • Wisconsin Stem Cell Research Institute, Inc., Madison, WI. Thirty cell pellets containing human embryonic stem cells were analyzed at 16 STR (Short Tandem Repeat) loci using the PowerPlex 16 BIO system (Promega Co., Madison, WI). The resulting DNA profiles were analyzed to determine the cell line’s genotype as well as its uniqueness and frequency in a given population.

 

  • Case Western Reserve University, Cleveland, OH. A two-year study was conducted on pairs of siblings who were concordant and discordant for diabetes and nephropathy. As part of the quality control efforts for this project, STR (Short Tandem Repeat) profiles were obtained from approximately 2600 individuals and compared to profiles from buffy coat DNA derived from an EDTA tube and to DNA extracted from immortalized B cell lines. Such comparisons allowed the research team to determine if potential errors occurred (i.e., the error rate) and the integrity of the study.